GUMS, GINGIVITIS & GENES
April 8th, 2010GUMS GINGIVITIS GENES
What’s the connection? Researchers at the University of North Carolina- Chapel Hill along with Procter & Gamble Oral Care published a report in the December 2009 Journal of Periodontology documenting a connection between swollen gums and the genetic code.
Traditionally when your dentist discussed with you that you had “swollen gums” he usually suggested you improve your oral hygiene habits; brush more, brush more effectively, floss more, remove plaque more effectively. It now appears that our ability to prevent and fight gum inflammation (gingivitis) may involve factors other than diligent brushing and flossing.
According to Dr. Steven Offenbacher, a lead researcher in the above study, over 9,000 genes (30% of the total genes in the body) are expressed differently during the onset and healing process of gingivitis. “Details of this discovery indicate that the same biological pathways that are associated with activation of the immune system are the major pathways activated during the body’s reaction to the buildup of plaque on the teeth” according to the AGD Impact news magazine(Feb, 2010) discussing the research. Furthermore “the gene expression pathways associated with thwarting plaque overgrowth are the same as those involved in wound healing and skin repair.” The genetics associated with gum inflammation and healing may therefore apply to other areas throughout the body.
Researchers are hoping that their understanding of gum inflammation on the molecular level will not only help clinicians eventually improve our understanding of prevention and treatment of gingivitis but will help others better understand and explain what is occurring in a person’s body at the onset of disease and how it relates to their overall health.
This study is just another that shows the increasing connection between dentistry and medicine and how clinicians and researchers are attempting to better understand the dental-medical connection.
As always-just my thoughts. Thanks for listening.
RMS